stop tb symposium
Accelerating impact : the transformative role of research to end tuberculosis
DATE: Wednesday, 30 October 2013
TIME: 09:00 - 18:00
ROOM: Amphithéâtre Bleu
The Stop TB Symposium is organised by the World Health Organization (WHO) and is open to all delegates; no badge is required to access the meeting room.
Who estimates that, in 2011, there were 8.7 million new tb cases in the world and that 1.4 million deaths occurred, including 430 000 among people who were hiv-positive. The mortality rate is declining steadily, and the stop tb partnership target of halving it by 2015 compared to 1990, will probably be reached globally, but not in all regions. The estimated tb incidence rate has been decreasing by about 2% per year since 2002. Projections show that at this pace of decline, elimination of tb (defined as less than 1 case per million population) will not be reached by 2050, while a further reduction in tb mortality is achievable over the next decades. In the past, dramatic declines in tb cases and deaths have been observed, for instance in western europe and north america after wwii, with an average incidence decline of 10%/year. A reference historical decline was observed among populations in alaska, nw canada and greenland from the mid-50s to the mid-70s, with an average rate of decline of 15%, due to the conjunction of highly focused interventions applying a full range of prevention and care efforts. Today, declines of about 4%/year are being observed in countries such as china and cambodia - but these rates are not sufficient to achieve the 2050 goal globally. Who is proposing new targets of a 95% reduction of tb mortality by 2035 worldwide (compared to 2015 levels) and a decline in incidence of new tb cases to below 10/100,000 population to end the global tb epidemic and then move towards tb elimination altogether. Reaching these targets will not be possible without the synergistic use of revolutionary treatment regimens for disease and latent infection and potent pre- and post-exposure vaccines, and the realization of universal health care access. This can be achieved only through a major intensification and broadening of research, with a multisectoral approach, and an integration of research and implementation efforts to enable “research for tb elimination”.
To highlight the crucial role of research in ending the global TB epidemic, "Intensified Research and Innovation" is the 3rd Pillar of the proposed Post 2015 TB Strategy developed by WHO, with broad consultation, that has 2 main components:
1. Discovery, development and rapid uptake of new tools, interventions and strategies
2. Research to optimise implementation and impact
Rapid Point-of-Care diagnostics, mass treatment of latent TB infection, potent short treatments, post and pre vaccines are highly needed. Basic research is fundamental to gain further knowledge needed to feed and transform the R&D pipeline. For this, we need to build coalitions of scientists, public health experts, NTP managers, donors, technical partners and civil society working in a translational and cross-cutting way to create examples of public health outcome-oriented research projects and achieve better integration of evidence-based tool discovery and subsequent interventions guided by clinical and affected community needs.
The process of developing the Research Pillar of the post-2015 TB Strategy has been initiated in a break-out session at the Stop TB Symposium in Kuala Lumpur in November 2012. This has been followed by a consultation of an array of stakeholders and an in-depth discussion with the WHO Strategic and Technical Advisory Group for Tuberculosis (STAG-TB) in June 2013 resulting in formulating possible strategies. In this symposium, the aim is to further the consultation process on how to ensure that research can help drive the world far faster to ending the epidemic and eventually eliminating TB altogether.
At the World Health Assembly 2012, Ministers of Health called on the World Health Organization to develop a post-2015 TB strategy and accompanying targets for their consideration in 2014. The World Health Organization, working with the Stop TB Partnership, has begun the process of developing the post-2015 TB strategy with an in-depth analysis of the drivers of the global TB epidemic, formulating possible new targets, preparing early drafts of the components and the content of the new strategy, and beginning wide consultation on the framework and targets. The WHO Strategic and Technical Advisory Group (STAG-TB) endorsed the approach and process for further development in June 2012 and a group of Stop TB Partners, including civil society and affected communities, met to provide first feedback. Consultation at regional meetings with National TB Programmes and others partners have begun. The Stop TB Symposium offers an outstanding opportunity to engage a large range of partners and viewpoints in discussing the work done to date and the way forward. The consultations in 2012 will inform further revision and finalisation of the strategy and targets in 2013 for subsequent endorsement, adoption and adaptation at country level.
Specific objectives of the Stop TB Symposium
(i) To inform and seek feedback from a wide range of stakeholders on the process of taking forward the Research Pillar of the post-2015 TB strategy and related targets
(ii) To discuss a potential framework for promotion of research aspects of the Strategy, for engagement of new partners and for widening the array of collaborations
Please click here to download the Stop TB Symposium programme as a PDF